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Wujin Sun

Assistant Professor

Education

Ph.D., Biomedical Engineering (Joint), The University of North Carolina at Chapel Hill & North Carolina State University, 2017

M.S., Biochemical Engineering, Nanjing Tech University, China, 2013

B.S., Bioengineering, Nanjing Tech University, China, 2010

Experience

September 2021 - Present, Assistant Professor, Department of Biological Systems Engineering, Virginia Tech, Blacksburg, VA

June 2020 - September 2021, Terasaki Fellow, Terasaki Institute for Biomedical Innovation, Los Angeles, CA

February 2018 - June 2020, Postdoctoral Scholar, Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA

In the Sun Lab, our research interest is at the interface between cell engineering and biomaterial engineering. We are interested in applying synthetic biology tools to engineer cells for therapeutic applications. We are also interested in developing drug delivery systems, such as nano-formulations, wearable devices, and injectable drug-releasing depots. In addition, we are interested in engineering tissue models for transplantation, disease modeling, or personalized prediction of therapeutic efficacy. We are interested in integrating synthetic biology, drug delivery, and tissue engineering techniques to design "Precision Medicine". 

Representative Publications:

*Corresponding author; #Equal contribution

[10] Luo Z,# Zhou X,# Mandal K,# He N, Wennerberg W, Qu M, Jiang X, Sun W,* Khademhosseini A.* Reconstructing the Tumor Architecture into Organoids. Advanced Drug Delivery Reviews. 2021; 176, 113839.

[9] Jiang X,# Ren L,# Tebon P,# Zhou X, Wang C, Qu M, Zhu J, Ashammakhi N, Ahadian S, Dokmeci MR, Gu Z, Sun W,* Khademhosseini A.* Cancer-on-a-Chip for Modeling Immune Checkpoint Inhibitor and Tumor Interactions. Small. 2021; 18, 2004282. 

[8] Ren L,# Zhou X,# Nasiri R,# Fang J, Jiang X, Wang C, Qu M, Ling H, Chen Y, Xue Y, Hartel M, Tebon P, Zhang S, Kim H, Yuan X, Shamloo A, Dokmeci MR, Li S, Khademhosseini A, Ahadian S,* Sun W.* Combined Effects of Electric Stimulation and Microgrooves in Cardiac Tissue-on-a-Chip for Drug Screening. Small Methods. 2020; 4, 2000438.

[7] Zhou X,# Jiang X,# Qu M,# Aninwene G, Jucaud V, Moon J, Gu Z, Sun W,* Khademhosseini A.* Engineering Antiviral Vaccines. ACS Nano. 2020; 14, 12370.

[6] Zhu J, Zhou X, Kim H, Qu M, Jiang X, Lee K, Ren L, Wu Q, Wang C, Zhu X, Tebon P, Zhang S, Lee J, Ashammakhi, Ahadian S, Dokmeci MR, Gu Z, Sun W,* Khademhosseini A.* Gelatin methacryloyl microneedle patches for minimally-invasive extraction of skin interstitial fluid. Small. 2020; 16, 1905910  (Highlighted as Cover)

[5] Sun W,* Wang J, Hu Q, Zhou X, Khademhosseini A, Gu Z.* CRISPR-Cas12a delivery by DNA-mediated bio-responsive editing for cholesterol regulation. Science Advances. 2020; 6: eaba2983.

[4] Sun W, Lee J, Zhang S, Benyshek C, Dokmeci MR, Khademhosseini A. Engineering Precision Medicine. Advanced Science 2018, 6: 1801039. (Highlighted as Front Cover)

[3] Sun W, Hu Q, Ji W, Wright G, Gu Z.* Leveraging Physiology for Precision Drug Delivery. Physiological Reviews 2017; 97: 189-225.

[2] Sun W, Ji W, Hall JM, Hu Q, Wang C, Beisel CL,* Gu Z.* Self‐Assembled DNA Nanoclews for the Efficient Delivery of CRISPR–Cas9 for Genome Editing. Angewandte Chemie International Edition 2015; 127: 12197-201. (Highlighted as Front Cover)

[1] Sun W, Jiang T, Lu Y, Reiff M, Mo R,* Gu Z.* Cocoon-like self-degradable DNA nanoclew for anticancer drug delivery. Journal of the American Chemical Society 2014; 136: 14722-5.